High resolution SPECT imaging for visualization of intratumoral heterogeneity using a SPECT/CT scanner dedicated for small animal imaging
نویسندگان
چکیده
منابع مشابه
Ultra-high-resolution small- animal SPECT imaging
Today the majority of clinical molecular imaging procedures are carried out with single photon emitters and gamma cameras, in planar mode and Single Photon Emission Computed Tomography (SPECT) mode. Thanks to the development of advanced multi-pinhole collimation technologies, SPECT imaging of small experimental animals is rapidly gaining in popularity. Whereas resolutions in routine clinical SP...
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Introduction: Image quality and accuracy of in vivo activity quantification in SPECT are affected by collimator penetration and scatter components, especially in high energy imaging. These phenomena highly depend on the collimator characteristic and photon energy. The presence of penetrated and scattered photons from collimator in SPECT images degrades spatial resolution, contr...
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The main objective of the present study was to upgrade a clinical gamma camera to obtain high resolution tomographic images of small animal organs. The system is based on a clinical gamma camera to which we have adapted a special-purpose pinhole collimator and a device for positioning and rotating the target based on a computer-controlled step motor. We developed a software tool to reconstruct ...
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ژورنال
عنوان ژورنال: Annals of Nuclear Medicine
سال: 2011
ISSN: 0914-7187,1864-6433
DOI: 10.1007/s12149-011-0542-7